Drug interactions
Devil's claw + Flurbiprofen
Severity: Minor
Devil's claw and Flurbiprofen: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw is reported to have mild antiplatelet effects and may add to the bleeding risk of NSAIDs. It is also used for pain, so the two are often taken together.
What this interaction means in plain words
Devil's claw and Flurbiprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; the mechanism of devil's claw is not well established.
What to do
Advise patients to report bleeding or black stools, and avoid the combination in patients with GI bleeding risk or on anticoagulants.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Frequently asked questions
Can I take Devil's claw with Flurbiprofen?
MediHelp rates the interaction as minor. Devil's claw and Flurbiprofen have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw is reported to have mild antiplatelet effects and may add to the bleeding risk of NSAIDs. It is also used for pain, so the two are often taken together.
How serious is the interaction between Devil's claw and Flurbiprofen?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to report bleeding or black stools, and avoid the combination in patients with GI bleeding risk or on anticoagulants.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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