Drug interactions
Devil's claw + Meclofenamic acid
Severity: Minor
Devil's claw and Meclofenamic acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has been linked to bleeding events and possible antiplatelet effects, and it is often taken for joint pain alongside NSAIDs. Combined use may add to gastrointestinal irritation and bleeding risk, though the evidence is limited.
What this interaction means in plain words
Devil's claw and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive antiplatelet effect; mechanism for devil's claw is not firmly established.
What to do
Ask patients about herbal use and discourage the combination in those at high bleeding risk. Monitor for gastrointestinal bleeding symptoms if both are continued.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Devil's claw and Meclofenamic acid, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Meclofenamic acid
- Ketorolac intranasal + Meclofenamic acid Contraindicated
- Ketorolac + Meclofenamic acid Contraindicated
- Aceclofenac + Meclofenamic acid Major
- Acemetacin + Meclofenamic acid Major
- Alteplase + Meclofenamic acid Major
- Amiloride + Meclofenamic acid Major
Frequently asked questions
Can I take Devil's claw with Meclofenamic acid?
MediHelp rates the interaction as minor. Devil's claw and Meclofenamic acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has been linked to bleeding events and possible antiplatelet effects, and it is often taken for joint pain alongside NSAIDs. Combined use may add to gastrointestinal irritation and bleeding risk, though the evidence is limited.
How serious is the interaction between Devil's claw and Meclofenamic acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask patients about herbal use and discourage the combination in those at high bleeding risk. Monitor for gastrointestinal bleeding symptoms if both are continued.
What other medicines interact with Meclofenamic acid?
MediHelp also lists interactions of Meclofenamic acid with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Meclofenamic acid page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
