Drug interactions
Devil's claw + Nateglinide
Severity: Minor
Devil's claw and Nateglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Devil's claw has shown glucose-lowering effects in animal studies. Taken with nateglinide it might add to the hypoglycemic effect, but human data are limited.
What this interaction means in plain words
Devil's claw and Nateglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hypoglycemic effect; the mechanism is not well established.
What to do
Monitor blood glucose if devil's claw is used with nateglinide and reduce the nateglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nateglinide
- Albiglutide + Nateglinide Moderate
- Alogliptin-metformin + Nateglinide Moderate
- Alogliptin-pioglitazone + Nateglinide Moderate
- Alogliptin + Nateglinide Moderate
- Alpelisib + Nateglinide Moderate
- Amiodarone + Nateglinide Moderate
Frequently asked questions
Can I take Devil's claw with Nateglinide?
MediHelp rates the interaction as minor. Devil's claw and Nateglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Devil's claw has shown glucose-lowering effects in animal studies. Taken with nateglinide it might add to the hypoglycemic effect, but human data are limited.
How serious is the interaction between Devil's claw and Nateglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose if devil's claw is used with nateglinide and reduce the nateglinide dose if hypoglycemia occurs.
What other medicines interact with Nateglinide?
MediHelp also lists interactions of Nateglinide with, for example, Albiglutide, Alogliptin-metformin, Alogliptin-pioglitazone. The full list is on the Nateglinide page.
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