Drug interactions
Dexamethasone + Influenza virus vaccine trivalent recombinant
Severity: Minor
Dexamethasone and Influenza virus vaccine trivalent recombinant: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Immunosuppressive doses of dexamethasone may reduce antibody response to the recombinant influenza vaccine. The vaccine is not live and can still be given.
What this interaction means in plain words
Dexamethasone and Influenza virus vaccine trivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Glucocorticoid immunosuppression reduces vaccine-induced humoral immune responses.
What to do
Give the vaccine as scheduled and do not withhold it, ideally before prolonged high-dose steroids when feasible.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dexamethasone
- Bcg vaccine live + Dexamethasone Contraindicated
- Dexamethasone + Mifepristone Contraindicated
- Dexamethasone + Rilpivirine Contraindicated
- Dexamethasone + Smallpox vaccine live Contraindicated
- Dexamethasone + Varicella virus vaccine live Contraindicated
- Dexamethasone + Yellow fever vaccine Contraindicated
Frequently asked questions
Can I take Dexamethasone with Influenza virus vaccine trivalent recombinant?
MediHelp rates the interaction as minor. Dexamethasone and Influenza virus vaccine trivalent recombinant have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Immunosuppressive doses of dexamethasone may reduce antibody response to the recombinant influenza vaccine. The vaccine is not live and can still be given.
How serious is the interaction between Dexamethasone and Influenza virus vaccine trivalent recombinant?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the vaccine as scheduled and do not withhold it, ideally before prolonged high-dose steroids when feasible.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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