Drug interactions
Dextroamphetamine + Oxazepam
Severity: Minor
Dextroamphetamine and Oxazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stimulants and benzodiazepines have opposing CNS effects, and the net result is unpredictable. Stimulant effects may mask sedation without removing the impairment caused by oxazepam.
What this interaction means in plain words
Dextroamphetamine and Oxazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dextroamphetamine belongs to Central Nervous System; Oxazepam belongs to Central Nervous System.
Why it happens
Opposing pharmacodynamic effects on CNS arousal; no significant pharmacokinetic interaction is established.
What to do
No routine adjustment is needed. Avoid using stimulants to counter benzodiazepine sedation and reassess the need for each drug.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Oxazepam
- Calcium / magnesium / potassium / sodium oxybates + Oxazepam Contraindicated
- Oxazepam + Sodium oxybate Contraindicated
- Alfentanil + Oxazepam Major
- Amobarbital + Oxazepam Major
- Baclofen + Oxazepam Major
- Belladonna and opium + Oxazepam Major
Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Oxazepam?
MediHelp rates the interaction as minor. Dextroamphetamine and Oxazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stimulants and benzodiazepines have opposing CNS effects, and the net result is unpredictable. Stimulant effects may mask sedation without removing the impairment caused by oxazepam.
How serious is the interaction between Dextroamphetamine and Oxazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Avoid using stimulants to counter benzodiazepine sedation and reassess the need for each drug.
What other medicines interact with Oxazepam?
MediHelp also lists interactions of Oxazepam with, for example, Calcium / magnesium / potassium / sodium oxybates, Sodium oxybate, Alfentanil. The full list is on the Oxazepam page.
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