Drug interactions
Dextroamphetamine + Salbutamol
Severity: Moderate
Dextroamphetamine and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dextroamphetamine is a sympathomimetic and salbutamol is a beta-2 agonist, so together they can add to tachycardia, palpitations, tremor and raised blood pressure. This is most relevant in patients with cardiovascular disease, hypertension or anxiety.
What this interaction means in plain words
Dextroamphetamine and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dextroamphetamine belongs to Central Nervous System; Salbutamol belongs to Respiratory.
Why it happens
Additive sympathomimetic stimulation of the cardiovascular system and central nervous system.
What to do
Monitor heart rate and blood pressure and reduce salbutamol use to the minimum effective dose. Review the amphetamine dose if palpitations, tremor or hypertension occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Dextroamphetamine
- Dextroamphetamine + Isocarboxazid Contraindicated
- Dextroamphetamine + Linezolid Contraindicated
- Dextroamphetamine + Methylene blue Contraindicated
- Dextroamphetamine + Phenelzine Contraindicated
- Dextroamphetamine + Rasagiline Contraindicated
- Dextroamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Dextroamphetamine with Salbutamol?
MediHelp rates the interaction as moderate. Dextroamphetamine and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dextroamphetamine is a sympathomimetic and salbutamol is a beta-2 agonist, so together they can add to tachycardia, palpitations, tremor and raised blood pressure. This is most relevant in patients with cardiovascular disease, hypertension or anxiety.
How serious is the interaction between Dextroamphetamine and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and blood pressure and reduce salbutamol use to the minimum effective dose. Review the amphetamine dose if palpitations, tremor or hypertension occur.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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