Drug interactions
Dichlorphenamide + Eribulin
Severity: Moderate
Dichlorphenamide and Eribulin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dichlorphenamide commonly causes hypokalemia, and eribulin can prolong the QT interval and cause electrolyte disturbances. Low potassium may increase the risk of QT-related arrhythmia.
What this interaction means in plain words
Dichlorphenamide and Eribulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dichlorphenamide belongs to Miscellaneous; Eribulin belongs to Oncology.
Why it happens
Dichlorphenamide causes renal potassium loss, and hypokalemia adds to eribulin's QT-prolonging effect.
What to do
Monitor serum potassium and magnesium and correct deficiencies; obtain ECG monitoring in patients with additional QT risk.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eribulin
Other interactions of Dichlorphenamide
Frequently asked questions
Can I take Dichlorphenamide with Eribulin?
MediHelp rates the interaction as moderate. Dichlorphenamide and Eribulin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dichlorphenamide commonly causes hypokalemia, and eribulin can prolong the QT interval and cause electrolyte disturbances. Low potassium may increase the risk of QT-related arrhythmia.
How serious is the interaction between Dichlorphenamide and Eribulin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and magnesium and correct deficiencies; obtain ECG monitoring in patients with additional QT risk.
What other medicines interact with Eribulin?
MediHelp also lists interactions of Eribulin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Eribulin page.
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