Drug interactions
Dichlorphenamide + Foscarnet
Severity: Moderate
Dichlorphenamide and Foscarnet: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs can lower serum potassium, and foscarnet also lowers magnesium and calcium. Combined use may cause significant hypokalemia, with a risk of arrhythmia and muscle weakness.
What this interaction means in plain words
Dichlorphenamide and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dichlorphenamide belongs to Miscellaneous; Foscarnet belongs to Anti Virals.
Why it happens
Additive potassium loss (renal wasting from carbonic anhydrase inhibition and foscarnet tubular effects).
What to do
Monitor serum potassium, magnesium, calcium and bicarbonate at baseline and regularly. Replace potassium as needed and consider ECG monitoring if levels fall.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Other interactions of Dichlorphenamide
Frequently asked questions
Can I take Dichlorphenamide with Foscarnet?
MediHelp rates the interaction as moderate. Dichlorphenamide and Foscarnet can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower serum potassium, and foscarnet also lowers magnesium and calcium. Combined use may cause significant hypokalemia, with a risk of arrhythmia and muscle weakness.
How serious is the interaction between Dichlorphenamide and Foscarnet?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium, magnesium, calcium and bicarbonate at baseline and regularly. Replace potassium as needed and consider ECG monitoring if levels fall.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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