Drug interactions
Dichlorphenamide + Morphine
Severity: Minor
Dichlorphenamide and Morphine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dichlorphenamide, a carbonic anhydrase inhibitor, lowers serum potassium and can cause metabolic acidosis, whereas morphine does not meaningfully lower potassium. No clinically relevant interaction is established.
What this interaction means in plain words
Dichlorphenamide and Morphine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dichlorphenamide belongs to Miscellaneous; Morphine belongs to Musculoskeletal.
Why it happens
No established pharmacokinetic or pharmacodynamic interaction; morphine's effect on potassium is not clinically significant.
What to do
No specific action is needed; monitor serum potassium and bicarbonate as routinely required for dichlorphenamide.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Morphine
- Alvimopan + Morphine Contraindicated
- Isocarboxazid + Morphine Contraindicated
- Morphine + Olanzapine / samidorphan Contraindicated
- Morphine + Phenelzine Contraindicated
- Morphine + Tranylcypromine Contraindicated
- Alfentanil + Morphine Major
Other interactions of Dichlorphenamide
Frequently asked questions
Can I take Dichlorphenamide with Morphine?
MediHelp rates the interaction as minor. Dichlorphenamide and Morphine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dichlorphenamide, a carbonic anhydrase inhibitor, lowers serum potassium and can cause metabolic acidosis, whereas morphine does not meaningfully lower potassium. No clinically relevant interaction is established.
How serious is the interaction between Dichlorphenamide and Morphine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor serum potassium and bicarbonate as routinely required for dichlorphenamide.
What other medicines interact with Morphine?
MediHelp also lists interactions of Morphine with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Morphine page.
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