Drug interactions
Dichlorphenamide + Nelfinavir
Severity: Minor
Dichlorphenamide and Nelfinavir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dichlorphenamide reliably causes metabolic acidosis, and nelfinavir has only rare association with lactic acidosis. Any additive acid-base effect is therefore speculative and not well documented.
What this interaction means in plain words
Dichlorphenamide and Nelfinavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Dichlorphenamide belongs to Miscellaneous; Nelfinavir belongs to Anti Virals.
Why it happens
Theoretical additive contribution to metabolic acidosis; no established mechanism.
What to do
Monitor serum bicarbonate periodically as recommended for dichlorphenamide. Evaluate promptly for acidosis if symptoms such as rapid breathing or malaise appear.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Dichlorphenamide
Other interactions of Nelfinavir
- Alfuzosin + Nelfinavir Contraindicated
- Avanafil + Nelfinavir Contraindicated
- Dronedarone + Nelfinavir Contraindicated
- Eletriptan + Nelfinavir Contraindicated
- Ergotamine + Nelfinavir Contraindicated
- Flibanserin + Nelfinavir Contraindicated
Frequently asked questions
Can I take Dichlorphenamide with Nelfinavir?
MediHelp rates the interaction as minor. Dichlorphenamide and Nelfinavir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dichlorphenamide reliably causes metabolic acidosis, and nelfinavir has only rare association with lactic acidosis. Any additive acid-base effect is therefore speculative and not well documented.
How serious is the interaction between Dichlorphenamide and Nelfinavir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum bicarbonate periodically as recommended for dichlorphenamide. Evaluate promptly for acidosis if symptoms such as rapid breathing or malaise appear.
What other medicines interact with Dichlorphenamide?
MediHelp also lists interactions of Dichlorphenamide with, for example, Acetazolamide, Acetylsalicylic acid, Ammonium chloride. The full list is on the Dichlorphenamide page.
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