Drug interactions
Dimenhydrinate + Hops
Severity: Moderate
Dimenhydrinate and Hops: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hops is used traditionally as a sedative and may add to the drowsiness caused by dimenhydrinate. This may reduce alertness and psychomotor performance.
What this interaction means in plain words
Dimenhydrinate and Hops can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive CNS depressant effects, possibly via GABAergic and melatonergic activity of hops constituents.
What to do
Counsel patients to avoid combining them when alertness is needed and to monitor for excess sedation. Stop the herbal product if drowsiness is excessive.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dimenhydrinate
Frequently asked questions
Can I take Dimenhydrinate with Hops?
MediHelp rates the interaction as moderate. Dimenhydrinate and Hops can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Hops is used traditionally as a sedative and may add to the drowsiness caused by dimenhydrinate. This may reduce alertness and psychomotor performance.
How serious is the interaction between Dimenhydrinate and Hops?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid combining them when alertness is needed and to monitor for excess sedation. Stop the herbal product if drowsiness is excessive.
What other medicines interact with Dimenhydrinate?
MediHelp also lists interactions of Dimenhydrinate with, for example, Belladonna and opium, Brexanolone, Calcium / magnesium / potassium / sodium oxybates. The full list is on the Dimenhydrinate page.
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