Drug interactions
Dipyridamole + Pindolol
Severity: Minor
Dipyridamole and Pindolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dipyridamole increases adenosine exposure, which depresses sinus and AV nodal function, and pindolol also lowers heart rate. The combination could produce bradycardia or conduction delay, particularly in susceptible patients.
What this interaction means in plain words
Dipyridamole and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive negative chronotropic and dromotropic effects from beta blockade and adenosine potentiation.
What to do
Monitor pulse and ECG in patients with baseline conduction disease or bradycardia. Reduce the beta blocker dose if symptomatic bradycardia develops.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Dipyridamole and Pindolol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Dipyridamole
- Dipyridamole + Riociguat Contraindicated
- Adenosine + Dipyridamole Major
- Betrixaban + Dipyridamole Major
- Dabigatran + Dipyridamole Major
- Dipyridamole + Regadenoson Major
- Dipyridamole + Venetoclax Major
Frequently asked questions
Can I take Dipyridamole with Pindolol?
MediHelp rates the interaction as minor. Dipyridamole and Pindolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Dipyridamole increases adenosine exposure, which depresses sinus and AV nodal function, and pindolol also lowers heart rate. The combination could produce bradycardia or conduction delay, particularly in susceptible patients.
How serious is the interaction between Dipyridamole and Pindolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor pulse and ECG in patients with baseline conduction disease or bradycardia. Reduce the beta blocker dose if symptomatic bradycardia develops.
What other medicines interact with Dipyridamole?
MediHelp also lists interactions of Dipyridamole with, for example, Riociguat, Adenosine, Betrixaban. The full list is on the Dipyridamole page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
