Drug interactions
Dobutamine + Ergoloid mesylates
Severity: Moderate
Dobutamine and Ergoloid mesylates: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ergoloid mesylates has relatively weak vasoconstrictor activity compared with other ergot alkaloids. Combined with dobutamine, an additive effect on blood pressure is possible but not well documented.
What this interaction means in plain words
Dobutamine and Ergoloid mesylates can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive pharmacodynamic effects on vascular tone and blood pressure.
What to do
Monitor blood pressure and heart rate during dobutamine infusion and titrate dose to effect. Consider holding ergoloid mesylates during acute inotropic therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dobutamine
Frequently asked questions
Can I take Dobutamine with Ergoloid mesylates?
MediHelp rates the interaction as moderate. Dobutamine and Ergoloid mesylates can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ergoloid mesylates has relatively weak vasoconstrictor activity compared with other ergot alkaloids. Combined with dobutamine, an additive effect on blood pressure is possible but not well documented.
How serious is the interaction between Dobutamine and Ergoloid mesylates?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate during dobutamine infusion and titrate dose to effect. Consider holding ergoloid mesylates during acute inotropic therapy.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
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