Drug interactions
Dobutamine + Formoterol
Severity: Moderate
Dobutamine and Formoterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs stimulate beta-adrenergic receptors, so combining them can increase heart rate, provoke tachyarrhythmias and lower serum potassium. The risk is greater in patients with ischemic heart disease or hemodynamic instability.
What this interaction means in plain words
Dobutamine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dobutamine belongs to Cardiovascular; Formoterol belongs to Respiratory.
Why it happens
Additive beta-adrenergic stimulation, with beta-2 mediated intracellular potassium shift.
What to do
Monitor ECG, heart rate, blood pressure and serum potassium during dobutamine infusion in patients using formoterol. Replace potassium as needed and consider holding formoterol if arrhythmias occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Dobutamine
Frequently asked questions
Can I take Dobutamine with Formoterol?
MediHelp rates the interaction as moderate. Dobutamine and Formoterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs stimulate beta-adrenergic receptors, so combining them can increase heart rate, provoke tachyarrhythmias and lower serum potassium. The risk is greater in patients with ischemic heart disease or hemodynamic instability.
How serious is the interaction between Dobutamine and Formoterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate, blood pressure and serum potassium during dobutamine infusion in patients using formoterol. Replace potassium as needed and consider holding formoterol if arrhythmias occur.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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