Drug interactions
Dobutamine + Indacaterol inhaled
Severity: Moderate
Dobutamine and Indacaterol inhaled: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Indacaterol is a long-acting beta-2 agonist, and labeling warns that other adrenergic drugs may potentiate its sympathetic effects. With dobutamine this can lead to tachycardia, arrhythmias, hypertension and hypokalemia.
What this interaction means in plain words
Dobutamine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-adrenergic stimulation.
What to do
Monitor heart rate, ECG, blood pressure and serum potassium while dobutamine is infused in patients using indacaterol. Reduce the dobutamine rate if tachyarrhythmia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Dobutamine
Frequently asked questions
Can I take Dobutamine with Indacaterol inhaled?
MediHelp rates the interaction as moderate. Dobutamine and Indacaterol inhaled can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Indacaterol is a long-acting beta-2 agonist, and labeling warns that other adrenergic drugs may potentiate its sympathetic effects. With dobutamine this can lead to tachycardia, arrhythmias, hypertension and hypokalemia.
How serious is the interaction between Dobutamine and Indacaterol inhaled?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, ECG, blood pressure and serum potassium while dobutamine is infused in patients using indacaterol. Reduce the dobutamine rate if tachyarrhythmia occurs.
What other medicines interact with Dobutamine?
MediHelp also lists interactions of Dobutamine with, for example, Budesonide-formoterol, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Dobutamine page.
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