Drug interactions
Docetaxel + Lumefantrine
Severity: Minor
Docetaxel and Lumefantrine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lumefantrine has been described as having weak CYP3A4 effects, but any influence on docetaxel is uncertain and likely small, particularly with a short antimalarial course.
What this interaction means in plain words
Docetaxel and Lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible weak modulation of CYP3A4; the mechanism is not well established.
What to do
No routine adjustment is needed. Monitor for docetaxel efficacy and toxicity.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Docetaxel and Lumefantrine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Docetaxel
Frequently asked questions
Can I take Docetaxel with Lumefantrine?
MediHelp rates the interaction as minor. Docetaxel and Lumefantrine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lumefantrine has been described as having weak CYP3A4 effects, but any influence on docetaxel is uncertain and likely small, particularly with a short antimalarial course.
How serious is the interaction between Docetaxel and Lumefantrine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor for docetaxel efficacy and toxicity.
What other medicines interact with Docetaxel?
MediHelp also lists interactions of Docetaxel with, for example, Adenovirus types 4 and 7 live, Atazanavir, Belatacept. The full list is on the Docetaxel page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
