Drug interactions
Docetaxel + Quercetin
Severity: Minor
Docetaxel and Quercetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin is a dietary supplement that modulates P-glycoprotein and CYP enzymes, and its effect on docetaxel is inconsistent and poorly established. Direction and size of any effect are uncertain.
What this interaction means in plain words
Docetaxel and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Variable modulation of P-glycoprotein and CYP3A4; the net effect on docetaxel is not well established.
What to do
Advise patients to avoid high-dose quercetin supplements during docetaxel therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Docetaxel
Frequently asked questions
Can I take Docetaxel with Quercetin?
MediHelp rates the interaction as minor. Docetaxel and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin is a dietary supplement that modulates P-glycoprotein and CYP enzymes, and its effect on docetaxel is inconsistent and poorly established. Direction and size of any effect are uncertain.
How serious is the interaction between Docetaxel and Quercetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid high-dose quercetin supplements during docetaxel therapy.
What other medicines interact with Docetaxel?
MediHelp also lists interactions of Docetaxel with, for example, Adenovirus types 4 and 7 live, Atazanavir, Belatacept. The full list is on the Docetaxel page.
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