Drug interactions
Dong quai + Flurbiprofen
Severity: Moderate
Dong quai and Flurbiprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type constituents and has been reported to potentiate anticoagulants. Combined with flurbiprofen's antiplatelet effect, bleeding risk may increase.
What this interaction means in plain words
Dong quai and Flurbiprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Theoretical additive effect of coumarin-like constituents of dong quai and NSAID platelet inhibition.
What to do
Advise patients to avoid dong quai while taking flurbiprofen, or monitor for bruising and bleeding if it is used.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Flurbiprofen
- Flurbiprofen + Ketorolac Contraindicated
- Flurbiprofen + Ketorolac intranasal Contraindicated
- Aceclofenac + Flurbiprofen Major
- Acemetacin + Flurbiprofen Major
- Acetylsalicylic acid + Flurbiprofen Major
- Alteplase + Flurbiprofen Major
Frequently asked questions
Can I take Dong quai with Flurbiprofen?
MediHelp rates the interaction as moderate. Dong quai and Flurbiprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents and has been reported to potentiate anticoagulants. Combined with flurbiprofen's antiplatelet effect, bleeding risk may increase.
How serious is the interaction between Dong quai and Flurbiprofen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while taking flurbiprofen, or monitor for bruising and bleeding if it is used.
What other medicines interact with Flurbiprofen?
MediHelp also lists interactions of Flurbiprofen with, for example, Ketorolac, Ketorolac intranasal, Aceclofenac. The full list is on the Flurbiprofen page.
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