Drug interactions
Dong quai + Ibuprofen
Severity: Moderate
Dong quai and Ibuprofen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type constituents and may have antiplatelet properties, so it might add to the bleeding tendency of ibuprofen. Clinical evidence is limited, mostly from case reports with warfarin.
What this interaction means in plain words
Dong quai and Ibuprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet and anticoagulant effects from coumarin constituents in dong quai with ibuprofen's platelet inhibition.
What to do
Advise patients to avoid dong quai while taking regular NSAIDs and monitor for bruising or bleeding if used together.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ibuprofen
- Ibuprofen + Ketorolac Contraindicated
- Ibuprofen + Ketorolac intranasal Contraindicated
- Acemetacin + Ibuprofen Major
- Alteplase + Ibuprofen Major
- Amiloride + Ibuprofen Major
- Apixaban + Ibuprofen Major
Frequently asked questions
Can I take Dong quai with Ibuprofen?
MediHelp rates the interaction as moderate. Dong quai and Ibuprofen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents and may have antiplatelet properties, so it might add to the bleeding tendency of ibuprofen. Clinical evidence is limited, mostly from case reports with warfarin.
How serious is the interaction between Dong quai and Ibuprofen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while taking regular NSAIDs and monitor for bruising or bleeding if used together.
What other medicines interact with Ibuprofen?
MediHelp also lists interactions of Ibuprofen with, for example, Ketorolac, Ketorolac intranasal, Acemetacin. The full list is on the Ibuprofen page.
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