Drug interactions
Dong quai + Naproxen
Severity: Moderate
Dong quai and Naproxen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type compounds and has been linked to increased bleeding risk. With naproxen the antiplatelet effect of the NSAID may be compounded.
What this interaction means in plain words
Dong quai and Naproxen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Coumarin constituents may add anticoagulant or antiplatelet effects to NSAID platelet inhibition.
What to do
Advise avoiding dong quai while taking naproxen long term. Monitor for bruising, bleeding and GI symptoms if used together.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Naproxen
- Ketorolac intranasal + Naproxen Contraindicated
- Ketorolac + Naproxen Contraindicated
- Aceclofenac + Naproxen Major
- Acemetacin + Naproxen Major
- Acetylsalicylic acid + Naproxen Major
- Alteplase + Naproxen Major
Frequently asked questions
Can I take Dong quai with Naproxen?
MediHelp rates the interaction as moderate. Dong quai and Naproxen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type compounds and has been linked to increased bleeding risk. With naproxen the antiplatelet effect of the NSAID may be compounded.
How serious is the interaction between Dong quai and Naproxen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding dong quai while taking naproxen long term. Monitor for bruising, bleeding and GI symptoms if used together.
What other medicines interact with Naproxen?
MediHelp also lists interactions of Naproxen with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Naproxen page.
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