Drug interactions
Dong quai + Tolmetin
Severity: Moderate
Dong quai and Tolmetin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dong quai contains coumarin-type constituents that may have anticoagulant or antiplatelet activity. With an NSAID that impairs platelet function, bleeding risk may be increased.
What this interaction means in plain words
Dong quai and Tolmetin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Possible additive antiplatelet or anticoagulant effects; the evidence is largely theoretical.
What to do
Advise patients to avoid dong quai while using tolmetin, or at least report any bruising or bleeding. Monitor for bleeding if both are continued.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tolmetin
- Ketorolac intranasal + Tolmetin Contraindicated
- Ketorolac + Tolmetin Contraindicated
- Aceclofenac + Tolmetin Major
- Acemetacin + Tolmetin Major
- Alteplase + Tolmetin Major
- Amlodipine-hydrochlorothiazide-valsartan + Tolmetin Major
Frequently asked questions
Can I take Dong quai with Tolmetin?
MediHelp rates the interaction as moderate. Dong quai and Tolmetin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dong quai contains coumarin-type constituents that may have anticoagulant or antiplatelet activity. With an NSAID that impairs platelet function, bleeding risk may be increased.
How serious is the interaction between Dong quai and Tolmetin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid dong quai while using tolmetin, or at least report any bruising or bleeding. Monitor for bleeding if both are continued.
What other medicines interact with Tolmetin?
MediHelp also lists interactions of Tolmetin with, for example, Ketorolac intranasal, Ketorolac, Aceclofenac. The full list is on the Tolmetin page.
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