Drug interactions
Dopexamine + Eprosartan-hydrochlorothiazide
Severity: Moderate
Dopexamine and Eprosartan-hydrochlorothiazide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopexamine is a beta-2 agonist used in critical care and may lower serum potassium, adding to the potassium loss from hydrochlorothiazide. Eprosartan tends to raise potassium, so the net effect is unpredictable.
What this interaction means in plain words
Dopexamine and Eprosartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Beta-2 mediated cellular potassium uptake combined with thiazide-induced renal potassium loss.
What to do
Monitor serum potassium during dopexamine infusion and replace as needed. Review diuretic and ARB dosing in unstable patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Dopexamine with Eprosartan-hydrochlorothiazide?
MediHelp rates the interaction as moderate. Dopexamine and Eprosartan-hydrochlorothiazide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopexamine is a beta-2 agonist used in critical care and may lower serum potassium, adding to the potassium loss from hydrochlorothiazide. Eprosartan tends to raise potassium, so the net effect is unpredictable.
How serious is the interaction between Dopexamine and Eprosartan-hydrochlorothiazide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium during dopexamine infusion and replace as needed. Review diuretic and ARB dosing in unstable patients.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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