Drug interactions
Dopexamine + Pseudoephedrine
Severity: Moderate
Dopexamine and Pseudoephedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopexamine is a hospital-administered catecholamine analogue, and adding an oral sympathomimetic could further increase heart rate and blood pressure and provoke arrhythmias. The effect matters mainly in critically ill or cardiac patients.
What this interaction means in plain words
Dopexamine and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive adrenergic stimulation from beta-2 and dopamine receptor agonism plus indirect sympathomimetic action.
What to do
Avoid giving pseudoephedrine during dopexamine infusion unless essential. Monitor hemodynamics and ECG continuously if both are given.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Pseudoephedrine
- Isocarboxazid + Pseudoephedrine Contraindicated
- Phenelzine + Pseudoephedrine Contraindicated
- Pseudoephedrine + Rasagiline Contraindicated
- Pseudoephedrine + Selegiline Contraindicated
- Pseudoephedrine + Selegiline transdermal Contraindicated
- Pseudoephedrine + Tranylcypromine Contraindicated
Frequently asked questions
Can I take Dopexamine with Pseudoephedrine?
MediHelp rates the interaction as moderate. Dopexamine and Pseudoephedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopexamine is a hospital-administered catecholamine analogue, and adding an oral sympathomimetic could further increase heart rate and blood pressure and provoke arrhythmias. The effect matters mainly in critically ill or cardiac patients.
How serious is the interaction between Dopexamine and Pseudoephedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving pseudoephedrine during dopexamine infusion unless essential. Monitor hemodynamics and ECG continuously if both are given.
What other medicines interact with Pseudoephedrine?
MediHelp also lists interactions of Pseudoephedrine with, for example, Isocarboxazid, Phenelzine, Rasagiline. The full list is on the Pseudoephedrine page.
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