Drug interactions
Dopexamine + Salmeterol
Severity: Moderate
Dopexamine and Salmeterol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Dopexamine is a beta-2 and dopaminergic agonist, so combining it with salmeterol gives additive beta-agonist effects including tachycardia, arrhythmia and hypokalemia. This matters mainly in acutely ill patients with cardiac compromise.
What this interaction means in plain words
Dopexamine and Salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive beta-2 adrenergic agonism, causing cardiac stimulation and intracellular potassium shift.
What to do
Monitor ECG, heart rate, blood pressure and serum potassium while dopexamine is infused. Reduce or stop salmeterol if tachyarrhythmia develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Dopexamine and Salmeterol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Salmeterol
- Ritonavir + Salmeterol Contraindicated
- Salmeterol + Saquinavir Contraindicated
- Amitriptyline + Salmeterol Major
- Arformoterol + Salmeterol Major
- Atazanavir + Salmeterol Major
- Budesonide-formoterol + Salmeterol Major
Frequently asked questions
Can I take Dopexamine with Salmeterol?
MediHelp rates the interaction as moderate. Dopexamine and Salmeterol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dopexamine is a beta-2 and dopaminergic agonist, so combining it with salmeterol gives additive beta-agonist effects including tachycardia, arrhythmia and hypokalemia. This matters mainly in acutely ill patients with cardiac compromise.
How serious is the interaction between Dopexamine and Salmeterol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, heart rate, blood pressure and serum potassium while dopexamine is infused. Reduce or stop salmeterol if tachyarrhythmia develops.
What other medicines interact with Salmeterol?
MediHelp also lists interactions of Salmeterol with, for example, Ritonavir, Saquinavir, Amitriptyline. The full list is on the Salmeterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
