Drug interactions
Doxorubicin + Mifamurtide
Severity: Moderate
Doxorubicin and Mifamurtide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mifamurtide is a liposomal product and doxorubicin is lipophilic, so concurrent dosing may alter distribution or the immune-stimulating effect of mifamurtide. Separate administration is advised to avoid this.
What this interaction means in plain words
Doxorubicin and Mifamurtide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxorubicin belongs to Oncology; Mifamurtide belongs to Miscellaneous.
Why it happens
Possible physicochemical or pharmacodynamic interaction between liposomal mifamurtide and lipophilic doxorubicin; not fully established.
What to do
Give mifamurtide at a different time from doxorubicin, separating the infusions as stated in the labeling.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Doxorubicin and Mifamurtide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Mifamurtide
- Cyclosporin + Mifamurtide Contraindicated
Other interactions of Doxorubicin
Frequently asked questions
Can I take Doxorubicin with Mifamurtide?
MediHelp rates the interaction as moderate. Doxorubicin and Mifamurtide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Mifamurtide is a liposomal product and doxorubicin is lipophilic, so concurrent dosing may alter distribution or the immune-stimulating effect of mifamurtide. Separate administration is advised to avoid this.
How serious is the interaction between Doxorubicin and Mifamurtide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give mifamurtide at a different time from doxorubicin, separating the infusions as stated in the labeling.
What other medicines interact with Mifamurtide?
MediHelp also lists interactions of Mifamurtide with, for example, Cyclosporin. The full list is on the Mifamurtide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
