Drug interactions
Doxorubicin + Valganciclovir
Severity: Moderate
Doxorubicin and Valganciclovir: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valganciclovir is converted to ganciclovir, which suppresses the bone marrow, as does doxorubicin. Combined use increases the risk of neutropenia, anemia and thrombocytopenia.
What this interaction means in plain words
Doxorubicin and Valganciclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Doxorubicin belongs to Oncology; Valganciclovir belongs to Anti Virals.
Why it happens
Additive myelosuppression.
What to do
Monitor complete blood counts frequently and reduce or interrupt either drug if cytopenias develop.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Valganciclovir
Other interactions of Doxorubicin
Frequently asked questions
Can I take Doxorubicin with Valganciclovir?
MediHelp rates the interaction as moderate. Doxorubicin and Valganciclovir can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Valganciclovir is converted to ganciclovir, which suppresses the bone marrow, as does doxorubicin. Combined use increases the risk of neutropenia, anemia and thrombocytopenia.
How serious is the interaction between Doxorubicin and Valganciclovir?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts frequently and reduce or interrupt either drug if cytopenias develop.
What other medicines interact with Valganciclovir?
MediHelp also lists interactions of Valganciclovir with, for example, Didanosine, Ganciclovir, Liposomal doxorubicin. The full list is on the Valganciclovir page.
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