Drug interactions
Drospirenone + Formoterol
Severity: Minor
Drospirenone and Formoterol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Formoterol can reduce serum potassium, while drospirenone has anti-mineralocorticoid activity and can raise it. The effects mostly counteract each other, so a significant change is uncommon, although potassium may shift in patients with renal impairment or on other potassium-affecting drugs.
What this interaction means in plain words
Drospirenone and Formoterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Drospirenone belongs to Endocrine; Formoterol belongs to Respiratory.
Why it happens
Opposing effects on serum potassium: beta2-mediated cellular uptake versus aldosterone antagonism reducing renal potassium loss.
What to do
No routine action is needed; monitor potassium if the patient has renal impairment or takes other drugs that alter potassium.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Formoterol
- Adagrasib + Formoterol Major
- Amiodarone + Formoterol Major
- Amisulpride + Formoterol Major
- Amitriptyline + Formoterol Major
- Amoxapine + Formoterol Major
- Arformoterol + Formoterol Major
Other interactions of Drospirenone
Frequently asked questions
Can I take Drospirenone with Formoterol?
MediHelp rates the interaction as minor. Drospirenone and Formoterol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Formoterol can reduce serum potassium, while drospirenone has anti-mineralocorticoid activity and can raise it. The effects mostly counteract each other, so a significant change is uncommon, although potassium may shift in patients with renal impairment or on other potassium-affecting drugs.
How serious is the interaction between Drospirenone and Formoterol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; monitor potassium if the patient has renal impairment or takes other drugs that alter potassium.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
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