Drug interactions
Echinacea + Ifosfamide
Severity: Minor
Echinacea and Ifosfamide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echinacea has immunostimulant properties that could theoretically oppose the effects of cytotoxic therapy. Clinical evidence of reduced ifosfamide efficacy is lacking.
What this interaction means in plain words
Echinacea and Ifosfamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Echinacea belongs to Gastrointestinal Tract; Ifosfamide belongs to Oncology.
Why it happens
Theoretical immune stimulation; no established pharmacokinetic or pharmacodynamic mechanism with ifosfamide.
What to do
Advise patients to avoid echinacea supplements during chemotherapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine Contraindicated
- Ifosfamide + Measles mumps and rubella vaccine live Contraindicated
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contraindicated
- Ifosfamide + Measles vaccine Contraindicated
- Ifosfamide + Rotavirus oral vaccine live Contraindicated
Other interactions of Echinacea
- Alefacept + Echinacea Moderate
- Antithymocyte globulin equine + Echinacea Moderate
- Antithymocyte globulin rabbit + Echinacea Moderate
- Azathioprine + Echinacea Moderate
- Basiliximab + Echinacea Moderate
- Cyclosporine + Echinacea Moderate
Frequently asked questions
Can I take Echinacea with Ifosfamide?
MediHelp rates the interaction as minor. Echinacea and Ifosfamide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Echinacea has immunostimulant properties that could theoretically oppose the effects of cytotoxic therapy. Clinical evidence of reduced ifosfamide efficacy is lacking.
How serious is the interaction between Echinacea and Ifosfamide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid echinacea supplements during chemotherapy.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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