Drug interactions
Echothiophate iodide + Galantamine
Severity: Moderate
Echothiophate iodide and Galantamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Echothiophate is an irreversible cholinesterase inhibitor and adds to the effect of galantamine. Systemic absorption can lead to cholinergic toxicity including bradycardia, bronchospasm, weakness and gastrointestinal symptoms.
What this interaction means in plain words
Echothiophate iodide and Galantamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive cholinesterase inhibition.
What to do
Monitor for signs of cholinergic excess, including heart rate and respiratory symptoms. Consider an alternative glaucoma therapy if systemic effects occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Galantamine
- Galantamine + Memantine-donepezil Major
- Galantamine + Physostigmine Major
- Galantamine + Ponesimod Major
- Galantamine + Rivastigmine Major
- Amifampridine + Galantamine Moderate
- Amiodarone + Galantamine Moderate
Frequently asked questions
Can I take Echothiophate iodide with Galantamine?
MediHelp rates the interaction as moderate. Echothiophate iodide and Galantamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Echothiophate is an irreversible cholinesterase inhibitor and adds to the effect of galantamine. Systemic absorption can lead to cholinergic toxicity including bradycardia, bronchospasm, weakness and gastrointestinal symptoms.
How serious is the interaction between Echothiophate iodide and Galantamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of cholinergic excess, including heart rate and respiratory symptoms. Consider an alternative glaucoma therapy if systemic effects occur.
What other medicines interact with Galantamine?
MediHelp also lists interactions of Galantamine with, for example, Memantine-donepezil, Physostigmine, Ponesimod. The full list is on the Galantamine page.
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