Drug interactions
Enoxaparin + Fenbufen
Severity: Moderate
Enoxaparin and Fenbufen: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Fenbufen is an NSAID that inhibits platelet function and can damage the gastric mucosa. With enoxaparin the risk of bleeding is increased, including gastrointestinal bleeding.
What this interaction means in plain words
Enoxaparin and Fenbufen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive hemostatic impairment from NSAID platelet inhibition and enoxaparin anticoagulation.
What to do
Avoid if possible, or use the lowest NSAID dose for the shortest time with monitoring for bleeding. Consider gastroprotection or paracetamol instead.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Fenbufen?
MediHelp rates the interaction as moderate. Enoxaparin and Fenbufen can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Fenbufen is an NSAID that inhibits platelet function and can damage the gastric mucosa. With enoxaparin the risk of bleeding is increased, including gastrointestinal bleeding.
How serious is the interaction between Enoxaparin and Fenbufen?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible, or use the lowest NSAID dose for the shortest time with monitoring for bleeding. Consider gastroprotection or paracetamol instead.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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