Drug interactions
Enoxaparin + Ginko biloba
Severity: Moderate
Enoxaparin and Ginko biloba: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ginkgo biloba may impair platelet function and add to the bleeding risk of enoxaparin. Evidence is limited to case reports and mechanistic reasoning, but spinal hematoma is a concern with neuraxial procedures.
What this interaction means in plain words
Enoxaparin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Ginko biloba belongs to Gastrointestinal Tract.
Why it happens
Ginkgo's platelet-activating factor antagonism adds antiplatelet effects to enoxaparin's anticoagulation.
What to do
Advise stopping ginkgo while on enoxaparin, especially around neuraxial anesthesia. Monitor for bleeding and bruising.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginko biloba
- Ginko biloba + Ketorolac Major
- Abciximab + Ginko biloba Moderate
- Aceclofenac + Ginko biloba Moderate
- Acemetacin + Ginko biloba Moderate
- Alteplase + Ginko biloba Moderate
- Anagrelide + Ginko biloba Moderate
Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Ginko biloba?
MediHelp rates the interaction as moderate. Enoxaparin and Ginko biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo biloba may impair platelet function and add to the bleeding risk of enoxaparin. Evidence is limited to case reports and mechanistic reasoning, but spinal hematoma is a concern with neuraxial procedures.
How serious is the interaction between Enoxaparin and Ginko biloba?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise stopping ginkgo while on enoxaparin, especially around neuraxial anesthesia. Monitor for bleeding and bruising.
What other medicines interact with Ginko biloba?
MediHelp also lists interactions of Ginko biloba with, for example, Ketorolac, Abciximab, Aceclofenac. The full list is on the Ginko biloba page.
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