Drug interactions
Enoxaparin + Horse chestnut seed
Severity: Minor
Enoxaparin and Horse chestnut seed: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Horse chestnut contains aescin and coumarin-type compounds that may have weak anticoagulant or antiplatelet effects. A modest increase in bleeding risk with enoxaparin is possible.
What this interaction means in plain words
Enoxaparin and Horse chestnut seed have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive effect from coumarin-type constituents and aescin.
What to do
Advise against use during anticoagulation. Monitor for bleeding if taken.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Horse chestnut seed?
MediHelp rates the interaction as minor. Enoxaparin and Horse chestnut seed have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Horse chestnut contains aescin and coumarin-type compounds that may have weak anticoagulant or antiplatelet effects. A modest increase in bleeding risk with enoxaparin is possible.
How serious is the interaction between Enoxaparin and Horse chestnut seed?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise against use during anticoagulation. Monitor for bleeding if taken.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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