Drug interactions
Enoxaparin + Pau d'arco
Severity: Minor
Enoxaparin and Pau d'arco: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Pau d'arco contains naphthoquinones such as lapachol, which may interfere with vitamin K and clotting. Its effect with enoxaparin is theoretical and poorly documented.
What this interaction means in plain words
Enoxaparin and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible anticoagulant effect from lapachol; not established.
What to do
Advise avoiding pau d'arco supplements during anticoagulation. Monitor for bleeding if used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Pau d'arco?
MediHelp rates the interaction as minor. Enoxaparin and Pau d'arco have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Pau d'arco contains naphthoquinones such as lapachol, which may interfere with vitamin K and clotting. Its effect with enoxaparin is theoretical and poorly documented.
How serious is the interaction between Enoxaparin and Pau d'arco?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise avoiding pau d'arco supplements during anticoagulation. Monitor for bleeding if used.
What other medicines interact with Enoxaparin?
MediHelp also lists interactions of Enoxaparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Enoxaparin page.
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