Drug interactions
Enoxaparin + Telmisartan-amlodipine
Severity: Moderate
Enoxaparin and Telmisartan-amlodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Enoxaparin can suppress aldosterone production and, with telmisartan, which also reduces aldosterone action, may raise serum potassium. Risk is greatest in renal impairment or diabetes.
What this interaction means in plain words
Enoxaparin and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Telmisartan-amlodipine belongs to Cardiovascular.
Why it happens
Heparin-induced reduction in aldosterone synthesis adds to angiotensin receptor blockade, decreasing potassium excretion.
What to do
Monitor potassium and renal function, particularly with prolonged enoxaparin use. Manage hyperkalemia if it develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan-amlodipine
- Aliskiren + Telmisartan-amlodipine Contraindicated
- Sparsentan + Telmisartan-amlodipine Contraindicated
- Amifostine + Telmisartan-amlodipine Major
- Amiloride + Telmisartan-amlodipine Major
- Benazepril + Telmisartan-amlodipine Major
- Candesartan + Telmisartan-amlodipine Major
Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Telmisartan-amlodipine?
MediHelp rates the interaction as moderate. Enoxaparin and Telmisartan-amlodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Enoxaparin can suppress aldosterone production and, with telmisartan, which also reduces aldosterone action, may raise serum potassium. Risk is greatest in renal impairment or diabetes.
How serious is the interaction between Enoxaparin and Telmisartan-amlodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor potassium and renal function, particularly with prolonged enoxaparin use. Manage hyperkalemia if it develops.
What other medicines interact with Telmisartan-amlodipine?
MediHelp also lists interactions of Telmisartan-amlodipine with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan-amlodipine page.
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