Drug interactions
Enoxaparin + Telmisartan
Severity: Moderate
Enoxaparin and Telmisartan: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Enoxaparin can suppress adrenal aldosterone secretion, and telmisartan blocks angiotensin II-driven aldosterone effects. Together they can cause clinically relevant hyperkalemia, particularly in patients with kidney disease or diabetes.
What this interaction means in plain words
Enoxaparin and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Enoxaparin belongs to Cardiovascular; Telmisartan belongs to Cardiovascular.
Why it happens
Additive reduction of aldosterone activity decreases renal potassium excretion.
What to do
Check serum potassium and renal function at baseline and periodically during combined use, particularly in prolonged courses or high-risk patients. Manage any hyperkalemia and remove other contributing drugs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telmisartan
- Aliskiren + Telmisartan Contraindicated
- Sparsentan + Telmisartan Contraindicated
- Amifostine + Telmisartan Major
- Amiloride + Telmisartan Major
- Amlodipine-benazepril + Telmisartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Telmisartan Major
Other interactions of Enoxaparin
- Defibrotide + Enoxaparin Contraindicated
- Enoxaparin + Ketorolac Contraindicated
- Enoxaparin + Mifepristone Contraindicated
- Abciximab + Enoxaparin Major
- Aceclofenac + Enoxaparin Major
- Acetylsalicylic acid + Enoxaparin Major
Frequently asked questions
Can I take Enoxaparin with Telmisartan?
MediHelp rates the interaction as moderate. Enoxaparin and Telmisartan can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Enoxaparin can suppress adrenal aldosterone secretion, and telmisartan blocks angiotensin II-driven aldosterone effects. Together they can cause clinically relevant hyperkalemia, particularly in patients with kidney disease or diabetes.
How serious is the interaction between Enoxaparin and Telmisartan?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium and renal function at baseline and periodically during combined use, particularly in prolonged courses or high-risk patients. Manage any hyperkalemia and remove other contributing drugs.
What other medicines interact with Telmisartan?
MediHelp also lists interactions of Telmisartan with, for example, Aliskiren, Sparsentan, Amifostine. The full list is on the Telmisartan page.
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