Drug interactions
Epinephrine racemic + Foscarnet
Severity: Minor
Epinephrine racemic and Foscarnet: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Racemic epinephrine is typically given by inhalation for airway swelling and has limited systemic exposure. Its QT effect is weak and foscarnet's QT effect is modest, so the clinical interaction is small. Catecholamine-induced hypokalemia could contribute slightly in susceptible patients.
What this interaction means in plain words
Epinephrine racemic and Foscarnet have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical additive QT effect, with beta-adrenergic hypokalemia as a possible contributor.
What to do
No routine change is needed. Monitor ECG and potassium in patients with existing QT risk factors or heavy epinephrine use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Foscarnet
- Cidofovir + Foscarnet Contraindicated
- Foscarnet + Pimozide Contraindicated
- Foscarnet + Thioridazine Contraindicated
- Foscarnet + Vandetanib Contraindicated
- Adagrasib + Foscarnet Major
- Adefovir + Foscarnet Major
Frequently asked questions
Can I take Epinephrine racemic with Foscarnet?
MediHelp rates the interaction as minor. Epinephrine racemic and Foscarnet have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Racemic epinephrine is typically given by inhalation for airway swelling and has limited systemic exposure. Its QT effect is weak and foscarnet's QT effect is modest, so the clinical interaction is small. Catecholamine-induced hypokalemia could contribute slightly in susceptible patients.
How serious is the interaction between Epinephrine racemic and Foscarnet?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed. Monitor ECG and potassium in patients with existing QT risk factors or heavy epinephrine use.
What other medicines interact with Foscarnet?
MediHelp also lists interactions of Foscarnet with, for example, Cidofovir, Pimozide, Thioridazine. The full list is on the Foscarnet page.
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