Drug interactions
Epinephrine racemic + Hydrochlorothiazide-telmisartan
Severity: Minor
Epinephrine racemic and Hydrochlorothiazide-telmisartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Racemic epinephrine stimulates beta-2 receptors and can lower serum potassium transiently. With thiazide-induced potassium loss, hypokalemia may be somewhat greater, and the pressor effect may oppose blood pressure control.
What this interaction means in plain words
Epinephrine racemic and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Beta-2 mediated cellular potassium uptake adds to renal potassium wasting from the thiazide.
What to do
Check serum potassium if repeated or high doses are used, particularly in patients with cardiac disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydrochlorothiazide-telmisartan
- Aliskiren + Hydrochlorothiazide-telmisartan Contraindicated
- Dofetilide + Hydrochlorothiazide-telmisartan Contraindicated
- Hydrochlorothiazide-telmisartan + Sparsentan Contraindicated
- Aldesleukin + Hydrochlorothiazide-telmisartan Major
- Amifostine + Hydrochlorothiazide-telmisartan Major
- Amiloride + Hydrochlorothiazide-telmisartan Major
Frequently asked questions
Can I take Epinephrine racemic with Hydrochlorothiazide-telmisartan?
MediHelp rates the interaction as minor. Epinephrine racemic and Hydrochlorothiazide-telmisartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Racemic epinephrine stimulates beta-2 receptors and can lower serum potassium transiently. With thiazide-induced potassium loss, hypokalemia may be somewhat greater, and the pressor effect may oppose blood pressure control.
How serious is the interaction between Epinephrine racemic and Hydrochlorothiazide-telmisartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum potassium if repeated or high doses are used, particularly in patients with cardiac disease.
What other medicines interact with Hydrochlorothiazide-telmisartan?
MediHelp also lists interactions of Hydrochlorothiazide-telmisartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Hydrochlorothiazide-telmisartan page.
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