Drug interactions
Epoprostenol + Ginger
Severity: Moderate
Epoprostenol and Ginger: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Epoprostenol is a potent platelet aggregation inhibitor and vasodilator, and ginger has mild antiplatelet activity. Together they could add to bleeding tendency, although evidence is theoretical.
What this interaction means in plain words
Epoprostenol and Ginger can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Epoprostenol belongs to Genitourinary; Ginger belongs to Gastrointestinal Tract.
Why it happens
Additive platelet inhibition, through raised platelet cAMP from epoprostenol and thromboxane synthesis inhibition from ginger.
What to do
Advise patients to avoid ginger supplements during epoprostenol therapy. Monitor for bleeding signs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ginger
- Aceclofenac + Ginger Moderate
- Acemetacin + Ginger Moderate
- Aescin + Ginger Moderate
- Aspirin / citric acid / sodium bicarbonate + Ginger Moderate
- Aspirin rectal + Ginger Moderate
- Aspirin + Ginger Moderate
Other interactions of Epoprostenol
- Acetylsalicylic acid + Epoprostenol Moderate
- Aescin + Epoprostenol Moderate
- Aldesleukin + Epoprostenol Moderate
- Alteplase + Epoprostenol Moderate
- Amlodipine-benazepril + Epoprostenol Moderate
- Amlodipine-hydrochlorothiazide-valsartan + Epoprostenol Moderate
Frequently asked questions
Can I take Epoprostenol with Ginger?
MediHelp rates the interaction as moderate. Epoprostenol and Ginger can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Epoprostenol is a potent platelet aggregation inhibitor and vasodilator, and ginger has mild antiplatelet activity. Together they could add to bleeding tendency, although evidence is theoretical.
How serious is the interaction between Epoprostenol and Ginger?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise patients to avoid ginger supplements during epoprostenol therapy. Monitor for bleeding signs.
What other medicines interact with Ginger?
MediHelp also lists interactions of Ginger with, for example, Aceclofenac, Acemetacin, Aescin. The full list is on the Ginger page.
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