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Drug interactions

Eprosartan-hydrochlorothiazide + Fo-ti

Severity: Minor

Eprosartan-hydrochlorothiazide and Fo-ti: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Fo-ti has been described as having laxative activity from anthraquinone content, which could contribute to potassium loss. Together with hydrochlorothiazide this could theoretically worsen hypokalemia, but clinical evidence is lacking.

What this interaction means in plain words

Eprosartan-hydrochlorothiazide and Fo-ti have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Theoretical additive potassium loss from laxative effect and thiazide diuresis.

What to do

Avoid prolonged use of fo-ti with the diuretic; check serum potassium if diarrhea or weakness develops.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Eprosartan-hydrochlorothiazide with Fo-ti?

MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Fo-ti have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Fo-ti has been described as having laxative activity from anthraquinone content, which could contribute to potassium loss. Together with hydrochlorothiazide this could theoretically worsen hypokalemia, but clinical evidence is lacking.

How serious is the interaction between Eprosartan-hydrochlorothiazide and Fo-ti?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid prolonged use of fo-ti with the diuretic; check serum potassium if diarrhea or weakness develops.

What other medicines interact with Eprosartan-hydrochlorothiazide?

MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.

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