Drug interactions
Eprosartan-hydrochlorothiazide + Ganciclovir
Severity: Minor
Eprosartan-hydrochlorothiazide and Ganciclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydrochlorothiazide might slightly reduce renal tubular secretion of ganciclovir, raising exposure. Volume depletion from the diuretic could further reduce renal clearance, increasing the risk of hematologic toxicity.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Eprosartan-hydrochlorothiazide belongs to Cardiovascular; Ganciclovir belongs to Anti Virals.
Why it happens
Possible competition for renal tubular secretion and reduced clearance from diuretic-related volume depletion.
What to do
Dose ganciclovir according to creatinine clearance and monitor blood counts and renal function.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Other interactions of Ganciclovir
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Ganciclovir?
MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Ganciclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydrochlorothiazide might slightly reduce renal tubular secretion of ganciclovir, raising exposure. Volume depletion from the diuretic could further reduce renal clearance, increasing the risk of hematologic toxicity.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Ganciclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Dose ganciclovir according to creatinine clearance and monitor blood counts and renal function.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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