Drug interactions
Eprosartan-hydrochlorothiazide + Insulin regular human
Severity: Moderate
Eprosartan-hydrochlorothiazide and Insulin regular human: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eprosartan may improve insulin sensitivity and potentiate the hypoglycemic effect of regular insulin. Hydrochlorothiazide may raise blood glucose and counteract insulin, causing unpredictable control.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Insulin regular human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
ARB-related improved insulin sensitivity versus thiazide-induced glucose intolerance.
What to do
Monitor blood glucose more closely after starting or changing the combination, and adjust the insulin dose accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Insulin regular human?
MediHelp rates the interaction as moderate. Eprosartan-hydrochlorothiazide and Insulin regular human can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eprosartan may improve insulin sensitivity and potentiate the hypoglycemic effect of regular insulin. Hydrochlorothiazide may raise blood glucose and counteract insulin, causing unpredictable control.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Insulin regular human?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose more closely after starting or changing the combination, and adjust the insulin dose accordingly.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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