Drug interactions
Eprosartan-hydrochlorothiazide + Olodaterol inhaled
Severity: Minor
Eprosartan-hydrochlorothiazide and Olodaterol inhaled: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Beta-2 agonists can lower serum potassium, and so does hydrochlorothiazide. The effect with inhaled olodaterol at recommended doses is usually small, but hypokalemia may be more pronounced with high doses or in patients with other risk factors.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Olodaterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive hypokalemia from beta-2 mediated cellular potassium uptake and thiazide-induced renal potassium loss.
What to do
Monitor serum potassium in patients with risk factors such as heart disease, hypoxia or high-dose therapy, and correct deficits.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Olodaterol inhaled?
MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Olodaterol inhaled have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Beta-2 agonists can lower serum potassium, and so does hydrochlorothiazide. The effect with inhaled olodaterol at recommended doses is usually small, but hypokalemia may be more pronounced with high doses or in patients with other risk factors.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Olodaterol inhaled?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients with risk factors such as heart disease, hypoxia or high-dose therapy, and correct deficits.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
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