Drug interactions
Eprosartan-hydrochlorothiazide + Penicillin g aqueous
Severity: Minor
Eprosartan-hydrochlorothiazide and Penicillin g aqueous: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both penicillin G and thiazides are eliminated partly through renal tubular secretion, so competition might modestly increase levels of either drug. Clinical significance is generally small, though high-dose penicillin G carries a sodium or potassium load and may cause electrolyte disturbance.
What this interaction means in plain words
Eprosartan-hydrochlorothiazide and Penicillin g aqueous have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible competition for renal tubular organic anion transport.
What to do
No routine dose change is needed; monitor electrolytes and renal function during high-dose or prolonged penicillin G therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Eprosartan-hydrochlorothiazide and Penicillin g aqueous, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Eprosartan-hydrochlorothiazide
- Aliskiren + Eprosartan-hydrochlorothiazide Contraindicated
- Dofetilide + Eprosartan-hydrochlorothiazide Contraindicated
- Eprosartan-hydrochlorothiazide + Sparsentan Contraindicated
- Aceclofenac + Eprosartan-hydrochlorothiazide Major
- Aldesleukin + Eprosartan-hydrochlorothiazide Major
- Amifostine + Eprosartan-hydrochlorothiazide Major
Frequently asked questions
Can I take Eprosartan-hydrochlorothiazide with Penicillin g aqueous?
MediHelp rates the interaction as minor. Eprosartan-hydrochlorothiazide and Penicillin g aqueous have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both penicillin G and thiazides are eliminated partly through renal tubular secretion, so competition might modestly increase levels of either drug. Clinical significance is generally small, though high-dose penicillin G carries a sodium or potassium load and may cause electrolyte disturbance.
How serious is the interaction between Eprosartan-hydrochlorothiazide and Penicillin g aqueous?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; monitor electrolytes and renal function during high-dose or prolonged penicillin G therapy.
What other medicines interact with Eprosartan-hydrochlorothiazide?
MediHelp also lists interactions of Eprosartan-hydrochlorothiazide with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Eprosartan-hydrochlorothiazide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
