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Drug interactions

Eptifibatide + Ginkgo biloba

Severity: Moderate

Eptifibatide and Ginkgo biloba: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ginkgo antagonizes platelet-activating factor and has been linked to bleeding reports. With eptifibatide, bleeding risk may rise, although controlled evidence is conflicting.

What this interaction means in plain words

Eptifibatide and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Evidence level: Low

Why it happens

Additive platelet inhibition from PAF antagonism and glycoprotein IIb/IIIa blockade.

What to do

Avoid ginkgo during eptifibatide therapy and ask about herbal use. Monitor for bleeding.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Eptifibatide with Ginkgo biloba?

MediHelp rates the interaction as moderate. Eptifibatide and Ginkgo biloba can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ginkgo antagonizes platelet-activating factor and has been linked to bleeding reports. With eptifibatide, bleeding risk may rise, although controlled evidence is conflicting.

How serious is the interaction between Eptifibatide and Ginkgo biloba?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ginkgo during eptifibatide therapy and ask about herbal use. Monitor for bleeding.

What other medicines interact with Eptifibatide?

MediHelp also lists interactions of Eptifibatide with, for example, Abrocitinib, Acalabrutinib, Acetylsalicylic acid. The full list is on the Eptifibatide page.

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