Drug interactions
Erdafitinib + Lamivudine
Severity: Minor
Erdafitinib and Lamivudine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Erdafitinib inhibits OCT2, and lamivudine is partly eliminated by renal cationic transport. Lamivudine exposure could rise modestly, though the effect is likely small.
What this interaction means in plain words
Erdafitinib and Lamivudine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Erdafitinib belongs to Oncology; Lamivudine belongs to Anti Virals.
Why it happens
Erdafitinib inhibition of OCT2-mediated renal tubular secretion of lamivudine.
What to do
No dose change is usually needed; monitor for lamivudine adverse effects in patients with renal impairment.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lamivudine
Other interactions of Erdafitinib
Frequently asked questions
Can I take Erdafitinib with Lamivudine?
MediHelp rates the interaction as minor. Erdafitinib and Lamivudine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Erdafitinib inhibits OCT2, and lamivudine is partly eliminated by renal cationic transport. Lamivudine exposure could rise modestly, though the effect is likely small.
How serious is the interaction between Erdafitinib and Lamivudine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is usually needed; monitor for lamivudine adverse effects in patients with renal impairment.
What other medicines interact with Lamivudine?
MediHelp also lists interactions of Lamivudine with, for example, Elvitegravir / cobicistat / emtricitabine / tenofovir df, Atidarsagene autotemcel, Betibeglogene autotemcel. The full list is on the Lamivudine page.
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