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Drug interactions

Eribulin + Levosalbutamol

Severity: Moderate

Eribulin and Levosalbutamol: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Eribulin can prolong the QT interval, and beta-2 agonists may add to this effect, especially if they cause hypokalemia. The additional risk with inhaled levosalbutamol at usual doses is likely modest.

What this interaction means in plain words

Eribulin and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Eribulin belongs to Oncology; Levosalbutamol belongs to Respiratory.

Evidence level: Low

Why it happens

Additive effects on cardiac repolarization, with beta-agonist-induced hypokalemia as a further contributing factor.

What to do

Check potassium and magnesium and correct deficits. Monitor ECG in patients receiving eribulin who need frequent or high-dose levosalbutamol.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Eribulin with Levosalbutamol?

MediHelp rates the interaction as moderate. Eribulin and Levosalbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin can prolong the QT interval, and beta-2 agonists may add to this effect, especially if they cause hypokalemia. The additional risk with inhaled levosalbutamol at usual doses is likely modest.

How serious is the interaction between Eribulin and Levosalbutamol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check potassium and magnesium and correct deficits. Monitor ECG in patients receiving eribulin who need frequent or high-dose levosalbutamol.

What other medicines interact with Levosalbutamol?

MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.

Full monographs, dosing and an interaction checker in the MediHelp app

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