Drug interactions
Eribulin + Octreotide
Severity: Moderate
Eribulin and Octreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eribulin carries a labeled risk of QT prolongation, and octreotide may add QT effects and bradycardia. The combination may raise arrhythmia risk, particularly with electrolyte abnormalities.
What this interaction means in plain words
Eribulin and Octreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eribulin belongs to Oncology; Octreotide belongs to Endocrine.
Why it happens
Additive pharmacodynamic QT prolongation.
What to do
Monitor ECG at baseline and periodically, and correct hypokalemia and hypomagnesemia. Reconsider therapy if QTc becomes markedly prolonged.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Octreotide
Other interactions of Eribulin
Frequently asked questions
Can I take Eribulin with Octreotide?
MediHelp rates the interaction as moderate. Eribulin and Octreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eribulin carries a labeled risk of QT prolongation, and octreotide may add QT effects and bradycardia. The combination may raise arrhythmia risk, particularly with electrolyte abnormalities.
How serious is the interaction between Eribulin and Octreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG at baseline and periodically, and correct hypokalemia and hypomagnesemia. Reconsider therapy if QTc becomes markedly prolonged.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
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