Drug interactions
Erlotinib + Quercetin
Severity: Minor
Erlotinib and Quercetin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quercetin may modulate P-glycoprotein and other transporters and could alter erlotinib absorption. The direction and size of the effect are uncertain and clinical relevance is unclear.
What this interaction means in plain words
Erlotinib and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible modulation of P-glycoprotein or BCRP transport by quercetin; the mechanism is not firmly established.
What to do
Counsel patients to avoid high-dose quercetin supplements during erlotinib therapy. Monitor response and tolerability if used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erlotinib
- Amobarbital + Erlotinib Major
- Apalutamide + Erlotinib Major
- Carbamazepine + Erlotinib Major
- Cobicistat + Erlotinib Major
- Darunavir + Erlotinib Major
- Dexlansoprazole + Erlotinib Major
Frequently asked questions
Can I take Erlotinib with Quercetin?
MediHelp rates the interaction as minor. Erlotinib and Quercetin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quercetin may modulate P-glycoprotein and other transporters and could alter erlotinib absorption. The direction and size of the effect are uncertain and clinical relevance is unclear.
How serious is the interaction between Erlotinib and Quercetin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to avoid high-dose quercetin supplements during erlotinib therapy. Monitor response and tolerability if used.
What other medicines interact with Erlotinib?
MediHelp also lists interactions of Erlotinib with, for example, Amobarbital, Apalutamide, Carbamazepine. The full list is on the Erlotinib page.
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