Drug interactions
Erythromycin + Eucalyptus
Severity: Minor
Erythromycin and Eucalyptus: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Eucalyptus oil is metabolized in part by CYP3A4 and may also induce it, so the interaction is poorly characterized. Erythromycin might raise eucalyptus constituent levels, but clinical consequences are not well documented.
What this interaction means in plain words
Erythromycin and Eucalyptus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible CYP3A4 inhibition by erythromycin affecting eucalyptus constituents; the clinical relevance is not established.
What to do
No specific action is needed; avoid ingesting concentrated eucalyptus oil, which is toxic.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Frequently asked questions
Can I take Erythromycin with Eucalyptus?
MediHelp rates the interaction as minor. Erythromycin and Eucalyptus have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Eucalyptus oil is metabolized in part by CYP3A4 and may also induce it, so the interaction is poorly characterized. Erythromycin might raise eucalyptus constituent levels, but clinical consequences are not well documented.
How serious is the interaction between Erythromycin and Eucalyptus?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; avoid ingesting concentrated eucalyptus oil, which is toxic.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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