Drug interactions
Erythromycin + Exemestane
Severity: Minor
Erythromycin and Exemestane: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Erythromycin may raise exemestane concentrations, but exemestane has a wide safety margin and a meaningful clinical effect is unlikely.
What this interaction means in plain words
Erythromycin and Exemestane have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Erythromycin belongs to Anti Bacterial; Exemestane belongs to Oncology.
Why it happens
Inhibition of CYP3A4-mediated metabolism of exemestane.
What to do
No dose adjustment is needed; monitor for increased adverse effects such as hot flushes or arthralgia.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Erythromycin
- Conivaptan + Erythromycin Contraindicated
- Dihydroergotamine intranasal + Erythromycin Contraindicated
- Dihydroergotamine + Erythromycin Contraindicated
- Domperidone + Erythromycin Contraindicated
- Dronedarone + Erythromycin Contraindicated
- Droperidol + Erythromycin Contraindicated
Other interactions of Exemestane
Frequently asked questions
Can I take Erythromycin with Exemestane?
MediHelp rates the interaction as minor. Erythromycin and Exemestane have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Erythromycin may raise exemestane concentrations, but exemestane has a wide safety margin and a meaningful clinical effect is unlikely.
How serious is the interaction between Erythromycin and Exemestane?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is needed; monitor for increased adverse effects such as hot flushes or arthralgia.
What other medicines interact with Erythromycin?
MediHelp also lists interactions of Erythromycin with, for example, Conivaptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Erythromycin page.
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